Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables Some transcripts contain a differentially

Some transcripts contain a differentially methylated region (DMR) at their 5' exons| and this DMR is commonly found in imprinted genes and correlates with transcript expression

Contains 6 Ig-like C2-type (immunoglobulin-like) domains

Contains 1 LEM-like domain

The encoded protein (CTD small phosphatase 1) plays a role in neuronal gene silencing in non-neuronal cells

Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables Some transcripts contain a differentiallyThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.