Bcl-2 Polyclonal Antibody, 50ul[BT-AP00860] Buffer Solutions Multiple family members are located

Multiple family members are located on the X chromosome

This gene is clustered with other MAGED genes on chromosome Xp11

a large family of proteins that regulate axon guidance

The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00860] Buffer Solutions Multiple family members are locatedBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.