TM55A Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes The SFPQ-NONO/SF-1 complex binds to

The SFPQ-NONO/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity

The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis

The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination

The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated

TM55A Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes The SFPQ-NONO/SF-1 complex binds toTMEM55A catalyzes the degradation of phosphatidylinositol 4 5 bisphosphate (PtdIns 4 5 P2) by removing the 4 phosphate (Ungewickell et al. 2005