MICA1 Rabbit Polyclonal Antibody, 20ul 3D Cell Culture Consumables Several alternatively spliced transcript variants

Several alternatively spliced transcript variants of this gene have been reported

This protein translocates from caveolae to the cytoplasm after insulin stimulation

A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon

Mutations in this gene are associated with early infantile epileptic encephalopathy

MICA1 Rabbit Polyclonal Antibody, 20ul 3D Cell Culture Consumables Several alternatively spliced transcript variantsThis gene encodes an enzyme that oxidizes methionine residues on actin thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9 CAS L (neural precursor cell expressed developmentally down regulated 9). Alternative splicing results in multiple transcript variants.