ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment Several alternatively spliced transcript variants

Several alternatively spliced transcript variants of FKRP have been described

The protein is active alone or as a heteromultimeric assembly with TRPC1| TRPC3| and TRPC4

This protein contains an actin filament-binding domain| which together with its Dbl homology domain and one of its pleckstrin homology domains| can form microspikes

and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region

ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment Several alternatively spliced transcript variantsThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of