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p53 Polyclonal Antibody, 20ul[BT-AP06825] Recombinant Protein Expression Alternatively spliced transcript variants encoding

SKU: 11043307912

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p53 Polyclonal Antibody, 20ul[BT-AP06825] Recombinant Protein Expression Alternatively spliced transcript variants encodingTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH

This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases

This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids

These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion

p53 Polyclonal Antibody, 20ul[BT-AP06825] Recombinant Protein Expression Alternatively spliced transcript variants encodingTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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