Flt3 Polyclonal Antibody, 100ul[BT-AP03283] Stepper constitute the high-affinity IL2 receptor

constitute the high-affinity IL2 receptor

This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system

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Two alternative transcripts encoding different isoforms have been identified

Flt3 Polyclonal Antibody, 100ul[BT-AP03283] Stepper constitute the high-affinity IL2 receptorFLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,