EFP Polyclonal Antibody, 50ul Vacuum Filter A mutation in the mouse

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

|subunit:Heterodimer of an alpha and a beta subunit

The transcript is expressed at high levels in the brain

and proliferation

EFP Polyclonal Antibody, 50ul Vacuum Filter A mutation in the mouseThe protein encoded by TRIM25 (tripartite motif containing 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the