RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging One of the isoforms (CXCR3-B)

One of the isoforms (CXCR3-B) shows high affinity binding to chemokine

Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas

This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA)

increased acidification produces increased proteolysis and efficient peptide loading

RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging One of the isoforms (CXCR3-B)RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions