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FoxE3 Polyclonal Antibody, 100ul Subcellular Fractions compared with normal lung

SKU: 11386261248

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FoxE3 Polyclonal Antibody, 100ul Subcellular Fractions compared with normal lungFOXE3 belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.

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Description

compared with normal lung

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

PTM:It is not sure whether N-glycosylation is on Asn-165 and/or Asn-166

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

FoxE3 Polyclonal Antibody, 100ul Subcellular Fractions compared with normal lungFOXE3 belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.

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