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Mouse Glutaredoxin-related Protein 5, Mitochondrial, GLRX5 ELISA Kit, 96T Filtration inhibits BMP2-mediated differentiation of osteoblasts

SKU: 12208682733

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Mouse Glutaredoxin-related Protein 5, Mitochondrial, GLRX5 ELISA Kit, 96T Filtration inhibits BMP2-mediated differentiation of osteoblastsMonothiol glutaredoxin involved in mitochondrial iron sulfur (Fe S) cluster transfer (PubMed: 19442627). Receives 2Fe 2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe FS cluster biosynthesis machinery, or export from mitochondrion (By similarity). Required for normal regulation of hemoglobin synthesis by the iron sulfur protein ACO1 (By similarity).

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Description

inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity)

and the kinase activity of the complex is regulated throughout the cell cycle mainly by fluctuating levels of Dbf4

which is known to lead to the demethylation of genomic DNA

PubMed: 15597323

Mouse Glutaredoxin-related Protein 5, Mitochondrial, GLRX5 ELISA Kit, 96T Filtration inhibits BMP2-mediated differentiation of osteoblastsMonothiol glutaredoxin involved in mitochondrial iron sulfur (Fe S) cluster transfer (PubMed: 19442627). Receives 2Fe 2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe FS cluster biosynthesis machinery, or export from mitochondrion (By similarity). Required for normal regulation of hemoglobin synthesis by the iron sulfur protein ACO1 (By similarity).

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