PXR Polyclonal Antibody, 50ul Lysosome Mutations in NODAL are associated

Mutations in NODAL are associated with heterotaxy

Unlock the full potential of your experiments with our Recombinant Trypsin Digestion Solution 10X

Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal

In receptor-expressing cells

PXR Polyclonal Antibody, 50ul Lysosome Mutations in NODAL are associatedThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including