S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies An alternatively spliced transcript variant

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

lys-bradykinin

the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult

The protein has also been found to have antimicrobial activity against bacteria| viruses and fungi

S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies An alternatively spliced transcript variantThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results