IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents SIGLEC5 encodes a member of

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family

Amplification and overexpression of this gene have been observed in several types of human carcinomas

It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid

tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents SIGLEC5 encodes a member ofIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants