Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions Changes in expression of this

Changes in expression of this gene have been linked to prostate cancer

The product of this gene functions to maintain the stability of dynein intermediate chain

thereby playing a key role in regulating the cellular redox environment

SERPINB5 is a Protein Coding gene

Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions Changes in expression of thisThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.