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HPS5 Polyclonal Antibody, 50ul Plasma Semaphorins are involved in numerous

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HPS5 Polyclonal Antibody, 50ul Plasma Semaphorins are involved in numerousThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha 3. Mutations in this gene are associated with Hermansky Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

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Description

Semaphorins are involved in numerous functions

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death

HPS5 Polyclonal Antibody, 50ul Plasma Semaphorins are involved in numerousThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha 3. Mutations in this gene are associated with Hermansky Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

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