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FAK(Phospho Tyr861) Polyclonal Antibody, 20ul sgRNA Oligos Mutations in this gene are

SKU: 14091890055

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FAK(Phospho Tyr861) Polyclonal Antibody, 20ul sgRNA Oligos Mutations in this gene areThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

Mutations in this gene are associated with sialuria

The protein has been shown to bind to the 5

The core complex associates with MTA2| MBD2| MBD3| MTA1L1| CHD3 and CHD4 to form the nucleosome remodeling and histone deacetylation (NuRD) complex| or with SIN3| SAP18 and SAP30 to form the SIN3 HDAC complex

translesion synthesis and lyase activity

FAK(Phospho Tyr861) Polyclonal Antibody, 20ul sgRNA Oligos Mutations in this gene areThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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