DLEC1 Polyclonal Antibody, 50ul Pathway and Network Analysis It appears to function as

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

Seems to negatively regulate the level of HIF1A expression

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase

Gene Ontology (GO) annotations related to this gene include calcium ion binding

DLEC1 Polyclonal Antibody, 50ul Pathway and Network Analysis It appears to function asThe cytogenetic location of DLEC1 (deleted in lung and esophageal cancer 1) is 3p21. , and it is located in a region that is commonly deleted in a variety of malignancies. Down regulation of DLEC1 has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of DLEC1 in tumor cells is a result of aberrant promoter methylation. Several alternatively