CD58 Polyclonal Antibody, 50ul[BT-AP01843] Antibody Humanization Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

GM-CSF and EPO in hematopoietic cells

CASP8 cleaves BH3-interacting domain death agonist

It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus

CD58 Polyclonal Antibody, 50ul[BT-AP01843] Antibody Humanization Several alternatively spliced transcript variantsCLDN2 (claudin 2) product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ specific manner and regulate tissue specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for CLDN2.