ARMCX3 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The heavy chain is approximately

The heavy chain is approximately 45 kDa and its gene contains 8 exons

Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers

the encoded protein can be a transcriptional activator or repressor

Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding

ARMCX3 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The heavy chain is approximatelyARMCX3 (armadillo repeat containing, X linked 3) encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. ARMCX3 is closely localized with other family members on the X chromosome. Three