IGF-IIR Polyclonal Antibody, 50ul[BT-AP04394] sgRNA Oligos Serine/threonine-protein kinase 10 can also

Serine/threonine-protein kinase 10 can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway

The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

IGF-IIR Polyclonal Antibody, 50ul[BT-AP04394] sgRNA Oligos Serine/threonine-protein kinase 10 can alsoIGF2R encodes a receptor for both insulin like growth factor 2 and mannose 6 phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with