TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This gene encodes a homeobox

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription

Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery

Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene

Variable expression of RPS5 in colorectal cancers compared to adjacent normal tissues has been observed

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging This gene encodes a homeoboxCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only