OTOGL Rabbit Polyclonal Antibody, 50ul Biochemical Reagents Eukaryotic translation initiation factor 2

Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by manganese ions and heparin

homologous to the HMG box of sex-determining region Y (SRY)

a calcium-binding protein related to tumor invasiveness and metastasis

The protein product of this gene

OTOGL Rabbit Polyclonal Antibody, 50ul Biochemical Reagents Eukaryotic translation initiation factor 2The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness.