PEK/PERK Polyclonal Antibody, 100ul Organelle Studies This protein has been shown

This protein has been shown to interact with

This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation

|PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity)

Belongs to the MMR1/HSR1 GTP-binding protein family

PEK/PERK Polyclonal Antibody, 100ul Organelle Studies This protein has been shownThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in