NPAP1 Rabbit Polyclonal Antibody, 20ul Cell Screening and Imaging Is thought to mediate docking

Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring

Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

and a proline-rich region

increased acidification produces increased proteolysis and efficient peptide loading

NPAP1 Rabbit Polyclonal Antibody, 20ul Cell Screening and Imaging Is thought to mediate dockingThis gene is located in the Prader Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader Willi syndrome.