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CLN3 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Upon activation by the cleavage

SKU: 16441036686

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CLN3 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Upon activation by the cleavageThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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Description

Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion

Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis

The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins

It is predominantly expressed in the ovary

CLN3 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Upon activation by the cleavageThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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