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Shc(Phospho Ser36) Polyclonal Antibody, 50ul Cell Proliferation Histamine is a ubiquitous messenger

SKU: 16478658964

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Shc(Phospho Ser36) Polyclonal Antibody, 50ul Cell Proliferation Histamine is a ubiquitous messengerThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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Description

Histamine is a ubiquitous messenger molecule released from mast cells

The protein encoded by PTPN6 (protein tyrosine phosphatase

Component of the PP4 complexes PPP4C-PPP4R1

Its activity is inhibited by spermine| sphingosine| and several phospholipids

Shc(Phospho Ser36) Polyclonal Antibody, 50ul Cell Proliferation Histamine is a ubiquitous messengerThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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