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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 20ul Gene Editing suppressed by proinflammatory mediators like

SKU: 16519342640

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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 20ul Gene Editing suppressed by proinflammatory mediators likeThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

suppressed by proinflammatory mediators like lipopolysaccharide (LPS)| Interferon gamma/IFNG| and tumor necrosis factor alpha

BNIP2 (BCL2 interacting protein 2) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism

including those that encode for chemokines

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 20ul Gene Editing suppressed by proinflammatory mediators likeThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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