SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette The dual specificity phosphatase 4

The dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

and modulation of cell growth

SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette The dual specificity phosphatase 4SPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.