P3C2B Polyclonal Antibody, 100ul RNA Tools Defects in this gene are

Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4)

Defects in this gene are the cause of Werner syndrome| an autosomal recessive disorder characterized by premature aging

particularly odontogenesis

Alternatively spliced transcript variants encoding different isoforms have been noted for this gene

P3C2B Polyclonal Antibody, 100ul RNA Tools Defects in this gene areThe protein encoded by this gene belongs to the phosphoinositide 3 kinase (PI3K) family. PI3 kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C terminal C2 domain, a characteristic of class II PI3 kinases. C2 domains act as calcium dependent phospholipid binding