Arkadia Polyclonal Antibody, 100ul Hepatocytes It participates in apoptosis signaling

It participates in apoptosis signaling through highly specific protein-protein homophilic interactions

In mouse| a similar pattern of expression was found

Overexpression of PBK has been implicated in tumorigenesis

cell cycle regulation and chromatin remodeling [PMID: 17486619]

Arkadia Polyclonal Antibody, 100ul Hepatocytes It participates in apoptosis signalingThe protein encoded by RNF111 (ring finger protein 111) is a nuclear RING domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) beta NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF beta target gene transcription. As a modulator of the nodal signaling cascade, RNF111 plays a critical role in the