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HIF-1 beta Polyclonal Antibody, 50ul[BT-AP09890] Endonucleases & Exonucleases HOXB2 is a member of

SKU: 17327517382

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SEK185.00 SEK232.00

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HIF-1 beta Polyclonal Antibody, 50ul[BT-AP09890] Endonucleases & Exonucleases HOXB2 is a member ofThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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Description

HOXB2 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain

Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A

The HLH motif is absolutely required for the induction of pseudohyphal growth in yeast and mediates heterodimerization with CASL

Plays a role in cardiomyocyte differentiation

HIF-1 beta Polyclonal Antibody, 50ul[BT-AP09890] Endonucleases & Exonucleases HOXB2 is a member ofThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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