MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis A pseudogene has been found

A pseudogene has been found on chromosome 1

Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues| many of these pathways are involved in the regulation of cell growth and differentiation

This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development

This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation

MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis A pseudogene has been foundMARCH4 is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.