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Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:

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Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:Functions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target

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Description

Deconjugates SUMO2 from MTA1 (PubMed: 21965678)

Dynamin-1 possesses unique mechanochemical properties used to tubulate and sever membranes

and makes up a large portion of endothelial cell intercellular junctions

Reduces hepatic gluconeogenesis through down-regulation of PEPCK in an isoform Alpha-dependent manner (PubMed: 26711253)

Rat Beta-Arrestin-2, ARRB2 ELISA Kit, 96T Cell Function Analysis Deconjugates SUMO2 from MTA1 (PubMed:Functions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target

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