c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 50ul Protein Research This protein negatively regulates skeletal

This protein negatively regulates skeletal muscle cell proliferation and differentiation

Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes

Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms

Mutations in this gene may be associated with sporatic cases of neural tube defects

c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 50ul Protein Research This protein negatively regulates skeletalThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a