PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Transcription factor required for TBX21/T-bet-dependent

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression

Defects in PAK3 are the cause of non-syndromic mental retardation X-linked type 30 (MRX30)

nuclear localization and membrane transport

is required for the apoptosis mediated by this protein

PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Transcription factor required for TBX21/T-bet-dependentThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene