HES5 Polyclonal Antibody, 100ul sgRNA customized design PAX1 is silenced by methylation

PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene

The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin

Mutations in this gene can cause X-linked eye disorders

RPL14 (ribosomal protein L14) encodes a ribosomal protein that is a component of the 60S subunit

HES5 Polyclonal Antibody, 100ul sgRNA customized design PAX1 is silenced by methylationThis gene encodes a member of a family of basic helix loop helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.