GLI-1 Polyclonal Antibody, 20ul Long RNA Synthesis The encoded protein is a

The encoded protein is a highly specific ubiquitin iso-peptidase

This protein may form oligomeric complexes with family members

subcellular location:Seems to be excluded from nucleoli

mutations in this gene are thought to confer a predisposition to sarcomas

GLI-1 Polyclonal Antibody, 20ul Long RNA Synthesis The encoded protein is aThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.