PIAS 3 Polyclonal Antibody, 50ul Metabolic enzymes Forms a ternary complex with

Forms a ternary complex with NF2/merlin and GRB2

The encoded protein mitochondrial ribosomal protein S18C is one of three that has significant sequence similarity to bacterial S18 proteins

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

as well as in peroxisomal reactions that consume 2-oxoglutarate

PIAS 3 Polyclonal Antibody, 50ul Metabolic enzymes Forms a ternary complex withPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.