Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 20ul Molecular Weight Markers Unleash your potential and conquer

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a region with homology to SMC chromosome segregation ATPases

This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3

This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis

Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 20ul Molecular Weight Markers Unleash your potential and conquerHuntingtin is a disease gene linked to Huntington's disease a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded unstable trinucleotide repeat in the huntingtin gene which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls and repeat numbers in excess of 40 have been described as