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PRAM7 Rabbit Polyclonal Antibody, 20ul Stepper Mutations in this gene are

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PRAM7 Rabbit Polyclonal Antibody, 20ul Stepper Mutations in this gene are

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Description

Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome

It is composed of three C2H2-type zinc-fingers

The encoded enzyme associates with AppBp1| an amyloid beta precursor protein binding protein| to form a heterodimer| and then the enzyme complex activates NEDD8| a ubiquitin-like protein| which regulates cell division| signaling and embryogenesis

Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas

PRAM7 Rabbit Polyclonal Antibody, 20ul Stepper Mutations in this gene are

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