ATF-2 Polyclonal Antibody, 50ul[BT-AP00694] Peptide Synthesis An alternatively spliced transcript variant

An alternatively spliced transcript variant of this gene may exist

where both Ser-425 and Ser-428 are phosphorylated at the onset of mitosis

The encoded protein functions as a transcriptional co-repressor

The encoded proteins binds to its own promoter as well as to that of several target genes

ATF-2 Polyclonal Antibody, 50ul[BT-AP00694] Peptide Synthesis An alternatively spliced transcript variantATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This