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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinase

SKU: 20456295451

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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinaseThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

The G protein-coupled receptor kinase 6 phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation

Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement

The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme

Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2)

JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes The G protein-coupled receptor kinaseThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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