RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene have

Mutations in this gene have been associated with limb-girdle muscular dystrophy

The ADAM metallopeptidase with thrombospondin type 1 motif 7 encoded by ADAMTS7 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family

ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins

2008 [PubMed 18310074])

RNase Z2 Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene haveThe protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST 1), and reduced expression can suppress transforming growth factor beta induced growth arrest. Mutations in ELAC2 result in an