Human Fibulin 5, FBLN5 ELISA Kit, 96T Custom DNA Oligos this gene product modulates apoptosis

this gene product modulates apoptosis in response to estrogen and tamoxifen

plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression

Human Fibulin 5, FBLN5 ELISA Kit, 96T Custom DNA Oligos this gene product modulates apoptosisEssential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed: 18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and