eIF2 alpha(Phospho Ser51) Polyclonal Antibody, 20ul DNA Fragments leading to neutrophil apoptosis

leading to neutrophil apoptosis

Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known

Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation

It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes

eIF2 alpha(Phospho Ser51) Polyclonal Antibody, 20ul DNA Fragments leading to neutrophil apoptosisThe translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36 kD EIF2 alpha subunit (EIF2S1), the 38 kD EIF2 beta subunit (EIF2S2; MIM 603908), and the 52 kD EIF2 gamma subunit (EIF2S3; MIM 300161). The rate of