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HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09891] Microbial Genome Editing This gene encodes a member

SKU: 21639270136

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HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09891] Microbial Genome Editing This gene encodes a memberThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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Description

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors

|enzyme regulation:Specifically inhibited by the intercalating agent amsacrine

Research also suggests that USP13 is implicated in the pathogenesis of melanoma through its ability to regulate the ubiquitination status of MITF

Localizes to centrosomes

HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09891] Microbial Genome Editing This gene encodes a memberThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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