Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter The encoded protein plays a

The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen

FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter The encoded protein plays aMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.