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MDM2 Polyclonal Antibody, 100ul[BT-AP05303] DNA/RNA Isolation & Purification also known as neur2 or

SKU: 21892102641

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MDM2 Polyclonal Antibody, 100ul[BT-AP05303] DNA/RNA Isolation & Purification also known as neur2 orMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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Description

also known as neur2 or NEURL3

Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses

Mouse studies suggest that this receptor is essential for normal male reproductive function

COPS2 is an essential component of the COP9 signalosome complex (CSN)

MDM2 Polyclonal Antibody, 100ul[BT-AP05303] DNA/RNA Isolation & Purification also known as neur2 orMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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