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CBX4 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Extraction also known as family 2

SKU: 22067476471

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SEK185.00 SEK209.00

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CBX4 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Extraction also known as family 2

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Description

also known as family 2 of ubiquitin carboxyl-terminal hydrolases

Members of this family are typically associated with the extracellular matrix

Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

CBX4 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Extraction also known as family 2

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